From chloroform to extract of meat: chemist and entrepreneur Liebig.

The correspondence of James Jurin (1684–1750): physician and secretary to the Royal Society

fundamental science, the boundaries of which he tried to extend from about 1840 into enterprises which he regarded as contiguous. In a series of thematic chapters we learn about Liebig's activities in industry, agriculture, physiology, pathology, and public health. He was thus the chemical gatekeeper of Brock's subtitle. He was also an effective popularizer of chemistry and a philosopher of sci...

Chronic chloroform intoxication.

Chloroform was discovered in 1831 by a French chemist, Soubeiran, and independently by the American, Samuel Guthrie of Sachett's Harbour, in the State ofNew York (Duncum, 1947). Soubeiran obtained impure chloroform, which he provisionally called " bichloric ether ", by distilling a mixture of chloride of lime and alcohol. Liebig, in the following year, obtained a purer chloroform, which he name...

Evaluation of the Extracts From Rhizomes of Polygonum bistorta for the Median Lethal Dosages in Swiss Albino Mice

Background: Polygonum bistorta has been used as a remedy for jaundice, smallpox, pimples, measles, cholera, diarrhoea, dysentery, expelling worms, insect stings and snakebites. In this study, the crude extract from P. bistorta and two fractions viz. hexane and chloroform obtained from the crude extract were studied for their median lethal dosages (LD50) in Swiss albino mice. Methods: Powdered ...

Carl Djerassi: Chemist and entrepreneur

Antitubercular Activity and Isolation of Chemical Constituents from plant Vitex negundo Linn.

Tuberculosis still remains a leading cause of death in the world. Currently considerable interest in natural products and their derivatives in the area of drug research for multidrug resistant tuberculosis (MDR-TB). The present investigation focused on identification, isolation, characterization of lead constituents and to determine the antitubercular activity of their enriched fractions and is...